Boss guides

Sanctum HM Solo Ranged

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Choose a Sanctum of Rebirth guide 6

Some guides predate Combat Modernization.

Guide versions

Guide illustration

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Introduction

This is an advanced guide and assumes a deep understanding of the boss's rotations and mechanics for the Hard Mode version of the Sanctum of Rebirth, found in Sanctum HM Mechanics Overview.

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Presets and Relics

⬥ Ranged range

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Vermyx, Brood Mother

Guide illustration

War's Retreat

wenarrows sgrico

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Phase 1

rgrico + grico → ecb eofspec + adrenrenewal → bolg spec → galeshot → deadshot → sgb eofspec → grico

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Coilspawn

Build 10 wenarrows → ecb eofspec → galeshot → dive to Vermyx

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Phase 2

rapid → improvise with bolg spec / dbow eofspec / snapshot / grico / gloomfirebow eofspec based on stacks

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Coilspawn

Build 12 deathsporearrows + 3-7 perfectequilibrium → gdeathsswift → dive to Vermyx

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Phase 3

fularrow imbueshadows → ecb eofspec → bolg spec → galeshot → rapid → deadshot → gloomfirebow eofspec → sgb eofspec → improvise

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Kezalam, the Wanderer

Guide illustration

War's Retreat

deathsporearrows sgrico

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Pre-fight (Moonstone Obelisk 1)

rgrico + grico → gdeathsswift → imbueshadows → fularrow ecb eofspec

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Phase 1

sbolg spec → rbolg spec + galeshot → rapid → deadshot → sgb eofspec → dbow eofspec

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Moonstone Obelisk 1

grico → shadowtend → snapshot / piercingshot → ecb eofspec → snipe

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Phase 2

galeshot → rapid → snapshot → dbow eofspec → grico → freedom → target moonstone + bolg spec → target kezalam + ingen + roarofawakening spec + adrenrenewal → build 12 deathsporearrows + 3 perfectequilibrium → gdeathsswift → fularrow imbueshadows → ecb eofspec → bolg spec → grico → snapshot / dbow eofspec if not phased

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Moonstone Obelisk 2

shadowtend → snapshot → ecb eofspec → snipe → grico

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Phase 3

galeshot → rapid → deadshot → sgb eofspec / gloomfirebow eofspec → improvise based on stacks

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Nakatra, Devourer Eternal

Guide illustration

⬥ Start on the east side to benefit from enchantmentofdread

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War's Retreat

deathsporearrows sdeadshot

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Phase 1

rdeadshot + grico → gdeathsswift → fularrow imbueshadows → ecb eofspec → bolg spec → galeshot → rapid → deadshot + nightmaregauntlets → gloomfirebow eofspec → grico → dbow eofspec + powerburstofvitality + disrupt → snapshot

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Phase 2

ecb eofspec → snipe → shadowtend → galeshot → rapid → dbow eofspec → grico → devo → bolg spec → divert → improvise until phased → ecb spec + adrenrenewal

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Phase 3

Nefthys 1

deadshot → grico → snapshot (may have to improvise based on stacks)

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Nefthys 2

galeshot → rapid → grico → snapshot → build adrenaline on Nakatra

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Phase 4

Shadowsands

decimation eofspec → grico → snipe → piercingshot → build wenarrows + deathsporearrows while doing this, ideally end on 3-7 perfectequilibrium or may have to improvise later

Note: decimation multiplies stack generation, be careful not to consume wenarrows on snipe

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Nakatra

deathsporearrows gdeathsswift → imbueshadows → ecb eofspec → fularrow bolg spec → galeshot → wenarrows rapid → deadshot → gloomfirebow eofspec → fularrow grico → snapshot → gloomfirebow eofspec → shadowtend → devo / reflect / divert + disrupt Magic hits → improvise

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Example Kills

⬥ Ranged range

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Source & licence

By PvME contributors under CC BY-NC-SA 4.0. Navigation and typography adapted. Unavailable source links and contributor names are labelled. Embedded media has separate rights.

Copied on 10 Nov 2026. Not rechecked against the current game.

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